Assessing the in vitro and in vivo toxicity of superparamagnetic iron oxide nanoparticles.
نویسندگان
چکیده
Oxide Nanoparticles Morteza Mahmoudi,* Heinrich Hofmann, Barbara Rothen-Rutishauser, and Alke Petri-Fink* Laboratory of Powder Technology, Ecole Polytechnique F ed erale de Lausanne, Lausanne, Switzerland (http://ltp.epfl.ch) National Cell Bank, Pasteur Institute of Iran, Tehran, Iran (www.biospion.com) Institute for Nanoscience and Nanotechnology Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran Adolphe Merkle Institute, University of Fribourg, 1700 Fribourg, Switzerland (www.am-institute.ch) Respiratory Medicine, Bern University Hospital, Inselspital, Freiburgstrasse, CH-3010 Bern, Switzerland Department of Chemistry, University of Fribourg, 1700 Fribourg, Switzerland (www.chem.unifr.ch)
منابع مشابه
Systematic review: Superparamagnetic Iron Oxide nanoparticles as contrast agents in diagnosis of multiple sclerosis
Several MRI contrast agents (CAs) are used in medical diagnosis that gadolinium (Gd3+) is the most widely used as contrast agents. Unfortunately, its toxicity is due to its inefficiency. In this review, we discuss about the ability of SPIONs in MRI and application in Multiple Sclerosis diagnosis. Superparamagnetic iron oxide nanoparticles (SPIONs) such as magnetite nanoparticles are used as goo...
متن کاملSystematic review: Superparamagnetic Iron Oxide nanoparticles as contrast agents in diagnosis of multiple sclerosis
Several MRI contrast agents (CAs) are used in medical diagnosis that gadolinium (Gd3+) is the most widely used as contrast agents. Unfortunately, its toxicity is due to its inefficiency. In this review, we discuss about the ability of SPIONs in MRI and application in Multiple Sclerosis diagnosis. Superparamagnetic iron oxide nanoparticles (SPIONs) such as magnetite nanoparticles are used as goo...
متن کاملThe acute toxicity of urea coated ferrous oxide nanoparticles on L929 cell line, evaluation of biochemical and pathological parameters in rat kidney and liver
Introduction: Iron plays an important role in physiological processes as a trace element. Today, iron oxide nanoparticles have attracted extensive attention due to their super paramagnetic properties and a variety of potential applications in many fields. The main objective of this study was to evaluate in vitro and in vivo toxic effects of the iron oxide nanoparticles on L929 cell line, kid...
متن کاملPreparation of polymer coated superparamagnetic Iron Oxide (Fe3O4) nanoparticles for biomedical application
Biomedical applications of superparamagnetic iron oxide nanoparticles (SPIONs) requiring precise control over their physical and magnetic properties, and proper surface treatment. Here we report a practical and effective electrochemical strategy for preparation of the polymer coated SPIONs. In this strategy, in situ polymer coating on the surface of SPIONs was achieved through electrodeposition...
متن کاملPreparation of polymer coated superparamagnetic Iron Oxide (Fe3O4) nanoparticles for biomedical application
Biomedical applications of superparamagnetic iron oxide nanoparticles (SPIONs) requiring precise control over their physical and magnetic properties, and proper surface treatment. Here we report a practical and effective electrochemical strategy for preparation of the polymer coated SPIONs. In this strategy, in situ polymer coating on the surface of SPIONs was achieved through electrodeposition...
متن کاملMagnetic iron oxide nanoparticles, Polyethylene glycol, Surfactant, Superparamagnetic, Chemical co-precipitation
In this study, magnetic iron oxide nanoparticles (Fe3O4) with the size range of 20-30 nm were prepared by the modified controlled chemical co-precipitation method from the solution of ferrous/ferric mixed salt-solution in alkaline medium. In this process polyethylene glycol was used as a surfactant to prevent the solution from agglomeration. The prepared magnetic nanoparticles were characterize...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Chemical reviews
دوره 112 4 شماره
صفحات -
تاریخ انتشار 2012